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Aseptic meningitis develops in patients receiving high-dose intravenous immunoglobulin therapy.Patients with a history of migraine are more likely to develop aseptic meningitis while receiving intravenous immunoglobulin therapy,regardless of the type of commercial preparation or the infusion rate.Possible inciting factors include the IgG itself,various stabilizing products within each of the preparations,cytokine release triggered by the therapy,or cerebrovascular sensitivity in migraineurs. |
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